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KIT disappeared on imatinib treatment (Blood 112: 1655, 2008).
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Hopefully nobody will biopsy it, but if you do, you’ll see little bleeds in the papillae, and mounds of parakeratosis.
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The cumulative risk of cutaneous malignancy is 10-30% at 5 years, 10-44% at 10 years, and 30-40% at 20 years.
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